Tropical Journal of Pharmaceutical Research

Original Research Article | OPEN ACCESS

Sodium Carboxymethyl Chitosan as a Fixative for Eau de Cologne

Surawut Wannaruemon^1,2, Ampa Jimtaisong¹ , Pornchai Rachtananpun^3,4

¹School of Cosmetic Science, Mae Fah Luang University, 333 Moo1, Thasud, Muang, Chiang Rai, 57100; ²Bangkok Perfumery, Co., Ltd., Muang, Nonthaburi 11000; ³Division of Packaging Technology, Faculty of Agro-Industry, Chiang Mai University, Muang, Chiang Mai 50100; ⁴Materials Science Research Center, Faculty of Science, Chiang Mai University 50200, Thailand.

For correspondence:- Ampa Jimtaisong Email: ampa@mfu.ac.th Tel:+6653916843

Received: 28 March 2012 Accepted: 12 December 2012 Published: 21 February 2013

Citation: Wannaruemon S, Jimtaisong A, Rachtananpun P. Sodium Carboxymethyl Chitosan as a Fixative for Eau de Cologne. Trop J Pharm Res 2013; 12(1):45-49 doi: 10.4314/tjpr.v12i1.8

© 2013 The authors.
This is an Open Access article that uses a funding model which does not charge readers or their institutions for access and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) and the Budapest Open Access Initiative (http://www.budapestopenaccessinitiative.org/read), which permit unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited..

Abstract

Purpose: To study the characteristics of sodium carboxymethyl chitosan (SCM-chitosan) as a fixative for eau de cologne product.

Methods: SCM-chitosan was prepared by carboxymethylation reaction of chitosan with monochloroacetic acid. The solubility of SCM-chitosan was investigated in water and ethanol. Sixteen perfume compounds which consisted of four chemical types - alcohols, ketones, aldehydes and ethers - were selected for eau de cologne preparation. The turbidity of the products prepared was monitored over 21-day aging period. Those showing no turbidity were selected for fixative studies with SCM-chitosan. The fixative effect of SCM-chitosan was evaluated by head space gas chromatography at different temperatures (25, 35 and 53 °C).

Results: The prepared SCM-chitosan was soluble in water but insoluble in ethanol. The optimum ratio between water and ethanol that could completely dissolve 0.1 % SCM-chitosan was 2:3 v/v. SCM-chitosan showed significant fixative effect (3.9 - 92.2 %) on p-cresyl methyl ether (10 % in dipropyleneglycol). Fixative efficiency increased from 3.9 % at 25°C to 42.1 % at 35 °C and 92.2 % at 53 °C. However, products containing benzyl alcohol, ethyl acetoacetate and 94085 floral-fruity showed precipitation after 21 days.

Conclusion: The results obtained indicate that SCM-chitosan could be used as a potential fixative for eau de cologne products.

Keywords: Biopolymer, carboxymethyl chitosan, cologne, fixative, perfume